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Chlorine dioxide (ClO2) is used to control bacterial slime and algae in industrial recirculating and one-pass cooling systems. The required dose of ClO2 will vary depending on the exact application and the degree of contamination present. The required chlorine dioxide residual concentrations range between 0.1 and 5.0 ppm. Chlorine dioxide may be applied either continuously or intermittently. The typical chlorine dioxide residual concentration range is 0.1 – 1.0 ppm for continuous doses and 0.1 – 5.0 ppm for intermittent doses. The minimum acceptable residual concentration of chlorine dioxide is 0.1 for a minimum one-minute contact time.

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